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G-protein Gα(13) functions as a cytoskeletal and mitochondrial regulator to restrain osteoclast function

Excessive osteoclastic bone erosion disrupts normal bone remodeling and leads to bone loss in many skeletal diseases, including inflammatory arthritis, such as rheumatoid arthritis (RA) and psoriatic arthritis, periodontitis and peri-prosthetic loosening. Functional control of osteoclasts is critica...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakano, Shinichi, Inoue, Kazuki, Xu, Cheng, Deng, Zhonghao, Syrovatkina, Viktoriya, Vitone, Gregory, Zhao, Liang, Huang, Xin-Yun, Zhao, Baohong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414604/
https://ncbi.nlm.nih.gov/pubmed/30862896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40974-z
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