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Contrasting in vitro and in vivo methanol oxidation activities of lanthanide-dependent alcohol dehydrogenases XoxF1 and ExaF from Methylobacterium extorquens AM1

Lanthanide (Ln) elements are utilized as cofactors for catalysis by XoxF-type methanol dehydrogenases (MDHs). A primary assumption is that XoxF enzymes produce formate from methanol oxidation, which could impact organisms that require formaldehyde for assimilation. We report genetic and phenotypic e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Good, Nathan M., Moore, Riley S., Suriano, Carly J., Martinez-Gomez, N. Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414531/
https://ncbi.nlm.nih.gov/pubmed/30862918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41043-1
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