CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement

Attachment of human adenovirus (HAd) to the host cell is a critical step of infection. Initial attachment occurs via the adenoviral fibre knob protein and a cellular receptor. Here we report the cryo-electron microscopy (cryo-EM) structure of a <100 kDa non-symmetrical complex comprising the trim...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Vassal-Stermann, Emilie, Effantin, Gregory, Zubieta, Chloe, Burmeister, Wim, Iseni, Frédéric, Wang, Hongjie, Lieber, André, Schoehn, Guy, Fender, Pascal
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414520/
https://ncbi.nlm.nih.gov/pubmed/30862836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09220-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items