GRA24-Based DNA Vaccine Prolongs Survival in Mice Challenged With a Virulent Toxoplasma gondii Strain

Toxoplasma gondii causes infections in a wide range of intermediate hosts and remains a threatening disease worldwide because of the lack of effective drugs and vaccines. Dense granule protein 24 (GRA24) is a novel essential virulence factor that is transferred into the nucleus of host cells from th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zheng, Bin, Lou, Di, Ding, Jianzu, Zhuo, Xunhui, Ding, Haojie, Kong, Qingming, Lu, Shaohong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414464/
https://ncbi.nlm.nih.gov/pubmed/30894865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00418
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