Essential role of JunD in cell proliferation is mediated via MYC signaling in prostate cancer cells

JunD, a member of the AP-1 family, is essential for cell proliferation in prostate cancer (PCa) cells. We recently demonstrated that JunD knock-down (KD) in PCa cells results in cell cycle arrest in G(1)-phase concomitant with a decrease in cyclin D1, Ki67, and c-MYC, but an increase in p21 levels....

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Elliott, Bethtrice, Millena, Ana Cecilia, Matyunina, Lilya, Zhang, Mengnan, Zou, Jin, Wang, Guangdi, Zhang, Qiang, Bowen, Nathan, Eaton, Vanessa, Webb, Gabrielle, Thompson, Shadyra, McDonald, John, Khan, Shafiq
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414252/
https://ncbi.nlm.nih.gov/pubmed/30763715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2019.02.005
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