A novel strategy of transferring NIS protein to cells using extracellular vesicles leads to increase in iodine uptake and cytotoxicity

BACKGROUND: This study was designed to explore a novel approach for transferring NIS protein to cells using extracellular vesicle (EV) and enhancing iodine avidity in hepatocellular carcinoma (HCC) cells. METHODS: We transfected the HCC cells (Huh7) with NIS gene, designated as Huh7/NIS, and isolate...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Son, Seung Hyun, Gangadaran, Prakash, Ahn, Byeong-Cheol
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413815/
https://ncbi.nlm.nih.gov/pubmed/30880979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S189738
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