Polypropylene mesh implantation for hernia repair causes myeloid cell–driven persistent inflammation

Polypropylene meshes that are commonly used for inguinal hernia repair may trigger granulomatous foreign body reactions. Here, we show that asymptomatic patients display mesh-associated inflammatory granulomas long after surgery, which are dominated by monocyte-derived macrophages expressing high le...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Heymann, Felix, von Trotha, Klaus-Thilo, Preisinger, Christian, Lynen-Jansen, Petra, Roeth, Anjali A., Geiger, Melanie, Geisler, Lukas Jonathan, Frank, Anna Katharina, Conze, Joachim, Luedde, Tom, Trautwein, Christian, Binnebösel, Marcel, Neumann, Ulf P., Tacke, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413778/
https://ncbi.nlm.nih.gov/pubmed/30674727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123862
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