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The effects of huntingtin-lowering: what do we know so far?

Therapies targeting mutant huntingtin DNA, mRNA, and protein have a chance at becoming the first disease-modifying treatments for Huntington’s disease, a fatal inherited neurodegenerative disorder for which only symptom management treatments are available today. This review focuses on evidence addre...

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Detalhes bibliográficos
Publicado no:Degener Neurol Neuromuscul Dis
Main Authors: Kaemmerer, William F, Grondin, Richard C
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413743/
https://ncbi.nlm.nih.gov/pubmed/30881191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DNND.S163808
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