Ultra-Sensitive CSF3R Deep Sequencing in Patients With Severe Congenital Neutropenia

High frequency of acquired CSF3R (colony stimulating factor 3 receptor, granulocyte) mutations has been described in patients with severe congenital neutropenia (CN) at pre-leukemia stage and overt acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Here, we report the establishment of a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Klimiankou, Maksim, Uenalan, Murat, Kandabarau, Siarhei, Nustede, Rainer, Steiert, Ingeborg, Mellor-Heineke, Sabine, Zeidler, Cornelia, Skokowa, Julia, Welte, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413711/
https://ncbi.nlm.nih.gov/pubmed/30891028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00116
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