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The mir‐465 family is upregulated with age and attenuates growth hormone signaling in mouse liver

We analyzed the small RNA transcriptome from 5‐month‐old, 24‐month‐old, and 36‐month‐old mouse liver and found 56 miRNAs that changed their expression profile with age. Among these is a cluster of 18 miRNAs that are upregulated between 50‐ and 1,000‐fold at 24 and 36 months of age. This cluster is l...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Elias, Amy E., Kun, Bianca, Sabula, Ian M. C., Golomb‐Mello, Gail, Cespedes Zablah, Andrea, Kreiling, Jill A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413667/
https://ncbi.nlm.nih.gov/pubmed/30637918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12892
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