Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts

BACKGROUND: Measures based on DNA methylation, epigenetic clocks, have recently gained attraction as predictors of mortality and age-related pathologies. However, the origins of variation in these measures are not well understood. METHODS: In a pooled sample of 104 Swedish and Danish twin pairs, we...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EBioMedicine
Prif Awduron: Jylhävä, Juulia, Hjelmborg, Jacob, Soerensen, Mette, Munoz, Elizabeth, Tan, Qihua, Kuja-Halkola, Ralf, Mengel-From, Jonas, Christensen, Kaare, Christiansen, Lene, Hägg, Sara, Pedersen, Nancy L., Reynolds, Chandra A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019
Pynciau:
Research paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413471/
https://ncbi.nlm.nih.gov/pubmed/30704927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.040
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