Simultaneous Determination of Five Chromones of Radix Saposhnikoviae Extract in Rat Plasma by UPLC-MS/MS: Application to a Comparative Pharmacokinetic Study in Normal and Febrile Rats

A rapid and sensitive quantitative analytical method was established for the simultaneous determination of five chromones (prim-O-glucosylcimifugin, cimifugin, 4′-O-β-D-glucosyl-5-O-methylvisamminol, 5-O-methylvisammiol, and sec-o-glucosylhamaudol) in the plasma of RS-treated rats for the first time...

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Dettagli Bibliografici
Pubblicato in:J Anal Methods Chem
Autori principali: Meng, Li, Gao, Hui, Chen, Bin, Liu, Peng-peng, Shan, Guo-shun, Zhang, Fan, Jia, Tian-zhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413363/
https://ncbi.nlm.nih.gov/pubmed/30937211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6454252
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