Specific knockdown of hippocampal astroglial EphB2 improves synaptic function via inhibition of D-serine secretion in APP/PS1 mice

Increasing evidence emphasizes the protective role of Eph receptors in synaptic function in the pathological development of Alzheimer’s disease (AD); however, their roles in the regulation of hippocampal astrocytes remain largely unknown. Here, we directly investigated the function of astroglial Eph...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Qi, Liang, Cui, En-Hui, Ji, Chun-Mei, Zhang, Xiao-Bing, Wang, Ze-Ai, Sun, Yuan-Zhao, Xu, Jian-Chang, Zhai, Xiao-Fu, Chen, Zhong-Jun, Li, Jing, Zheng, Jin-Yu, Yu, Ru-Tong
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413293/
https://ncbi.nlm.nih.gov/pubmed/30899407
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