Hydroxyethyl Starch 130/0.4 Binds to Neutrophils Impairing Their Chemotaxis through a Mac-1 Dependent Interaction

Several studies showed that hydroxyethyl starch (HES), a synthetic colloid used in volume replacement therapies, interferes with leukocyte-endothelium interactions. Although still unclear, the mechanism seems to involve the inhibition of neutrophils’ integrin. With the aim to provide direct evidence...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Trentini, Alessandro, Murganti, Francesca, Rosta, Valentina, Cervellati, Carlo, Manfrinato, Maria Cristina, Spadaro, Savino, Dallocchio, Franco, Volta, Carlo Alberto, Bellini, Tiziana
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413098/
https://ncbi.nlm.nih.gov/pubmed/30769810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040817
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