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Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid

Vitamins B9 (folate) and B12 act as methyl donors in the one-carbon metabolism which influences epigenetic mechanisms. We previously showed that an embryofetal deficiency of vitamins B9 and B12 in the rat increased brain expression of let-7a and miR-34a microRNAs involved in the developmental contro...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Geoffroy, Andréa, Saber-Cherif, Lynda, Pourié, Grégory, Helle, Déborah, Umoret, Rémy, Guéant, Jean-Louis, Bossenmeyer-Pourié, Carine, Daval, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413039/
https://ncbi.nlm.nih.gov/pubmed/30813413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040973
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