Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation

BACKGROUND: Ubiquinol-cytochrome C reductase core protein II (QCR2) is essential for mitochondrial functions, yet, its role in cancer development has remained elusive. METHODS: The expression of QCR2 in cancer patients was assessed by immunohistochemistry. The proliferation of cancer cells was asses...

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Gepubliceerd in:EBioMedicine
Hoofdauteurs: Han, Yingyan, Wu, Peng, Wang, Zhi, Zhang, Zeyu, Sun, Shujuan, Liu, Jia, Gong, Song, Gao, Peipei, Iwakuma, Tomoo, Molina-Vila, Miguel Angel, Chen, Benjamin Ping-Chi, Zhang, Yu, Ji, Teng, Mo, Qingqing, Chen, Pingbo, Hu, Junbo, Wang, Shixuan, Zhou, Jianfeng, Lu, Hua, Gao, Qinglei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2019
Onderwerpen:
Research paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412871/
https://ncbi.nlm.nih.gov/pubmed/30674441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.002
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