Endoplasmic Reticulum Stress and Unfolded Protein Response in Breast Cancer: The Balance between Apoptosis and Autophagy and Its Role in Drug Resistance

The unfolded protein response (UPR) is a stress response activated by the accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum (ER) and its uncontrolled activation is mechanistically responsible for several human pathologies, including metabolic, neurodegenerative...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sisinni, Lorenza, Pietrafesa, Michele, Lepore, Silvia, Maddalena, Francesca, Condelli, Valentina, Esposito, Franca, Landriscina, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412864/
https://ncbi.nlm.nih.gov/pubmed/30781465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040857
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