Endoplasmic Reticulum Stress and Unfolded Protein Response in Breast Cancer: The Balance between Apoptosis and Autophagy and Its Role in Drug Resistance

The unfolded protein response (UPR) is a stress response activated by the accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum (ER) and its uncontrolled activation is mechanistically responsible for several human pathologies, including metabolic, neurodegenerative...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Sisinni, Lorenza, Pietrafesa, Michele, Lepore, Silvia, Maddalena, Francesca, Condelli, Valentina, Esposito, Franca, Landriscina, Matteo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412864/
https://ncbi.nlm.nih.gov/pubmed/30781465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040857
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