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The Phenotype of Celiac Disease Has Low Concordance between Siblings, Despite a Similar Distribution of HLA Haplotypes

The factors determining the presentation of celiac disease are unclear. We investigated the phenotypic concordance and the distribution of human leukocyte antigen (HLA) risk haplotypes in affected siblings. One hundred sibling pairs were included. Clinical and histological parameters and HLA haploty...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Kauma, Saana, Kaukinen, Katri, Huhtala, Heini, Kivelä, Laura, Pekki, Henna, Salmi, Teea, Saavalainen, Päivi, Lindfors, Katri, Kurppa, Kalle
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412523/
https://ncbi.nlm.nih.gov/pubmed/30823533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11020479
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