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Hyaluronic acid inhibition by 4-methylumbelliferone reduces the expression of cancer stem cells markers during hepatocarcinogenesis

Hyaluronic acid (HA) is a glycosaminoglycan of extracellular matrix related to cell surface which interacts with various cell types. To understand the role of HA during hepatocarcinogenesis, we assessed the effect of the inhibition of HA deposition and its association with heterogeneous hepatocellul...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Sukowati, Caecilia H. C., Anfuso, Beatrice, Fiore, Esteban, Ie, Susan I., Raseni, Alan, Vascotto, Fulvia, Avellini, Claudio, Mazzolini, Guillermo, Tiribelli, Claudio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411988/
https://ncbi.nlm.nih.gov/pubmed/30858465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40436-6
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