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Hyaluronic acid inhibition by 4-methylumbelliferone reduces the expression of cancer stem cells markers during hepatocarcinogenesis

Hyaluronic acid (HA) is a glycosaminoglycan of extracellular matrix related to cell surface which interacts with various cell types. To understand the role of HA during hepatocarcinogenesis, we assessed the effect of the inhibition of HA deposition and its association with heterogeneous hepatocellul...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Sukowati, Caecilia H. C., Anfuso, Beatrice, Fiore, Esteban, Ie, Susan I., Raseni, Alan, Vascotto, Fulvia, Avellini, Claudio, Mazzolini, Guillermo, Tiribelli, Claudio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411988/
https://ncbi.nlm.nih.gov/pubmed/30858465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40436-6
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