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Isolation and genome-wide characterization of cellular DNA:RNA triplex structures

RNA can directly bind to purine-rich DNA via Hoogsteen base pairing, forming a DNA:RNA triple helical structure that anchors the RNA to specific sequences and allows guiding of transcription regulators to distinct genomic loci. To unravel the prevalence of DNA:RNA triplexes in living cells, we have...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Sentürk Cetin, Nevcin, Kuo, Chao-Chung, Ribarska, Teodora, Li, Ronghui, Costa, Ivan G, Grummt, Ingrid
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411930/
https://ncbi.nlm.nih.gov/pubmed/30605520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1305
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