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Tissue-specific extracellular matrix accelerates the formation of neural networks and communities in a neuron-glia co-culture on a multi-electrode array

The brain’s extracellular matrix (ECM) is a macromolecular network composed of glycosaminoglycans, proteoglycans, glycoproteins, and fibrous proteins. In vitro studies often use purified ECM proteins for cell culture coatings, however these may not represent the molecular complexity and heterogeneit...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Lam, Doris, Enright, Heather A., Cadena, Jose, Peters, Sandra K. G., Sales, Ana Paula, Osburn, Joanne J., Soscia, David A., Kulp, Kristen S., Wheeler, Elizabeth K., Fischer, Nicholas O.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411890/
https://ncbi.nlm.nih.gov/pubmed/30858401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40128-1
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