PGC-1α overexpression partially rescues impaired oxidative and contractile pathophysiology following volumetric muscle loss injury

Volumetric muscle loss (VML) injury is characterized by a non-recoverable loss of muscle fibers due to ablative surgery or severe orthopaedic trauma, that results in chronic functional impairments of the soft tissue. Currently, the effects of VML on the oxidative capacity and adaptability of the rem...

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Pubblicato in:Sci Rep
Autori principali: Southern, William M., Nichenko, Anna S., Tehrani, Kayvan F., McGranahan, Melissa J., Krishnan, Laxminarayanan, Qualls, Anita E., Jenkins, Nathan T., Mortensen, Luke J., Yin, Hang, Yin, Amelia, Guldberg, Robert E., Greising, Sarah M., Call, Jarrod A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411870/
https://ncbi.nlm.nih.gov/pubmed/30858541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40606-6
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