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Alterations in the tyrosine and phenylalanine pathways revealed by biochemical profiling in cerebrospinal fluid of Huntington’s disease subjects

Huntington’s disease (HD) is a severe neurological disease leading to psychiatric symptoms, motor impairment and cognitive decline. The disease is caused by a CAG expansion in the huntingtin (HTT) gene, but how this translates into the clinical phenotype of HD remains elusive. Using liquid chromatog...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Herman, Stephanie, Niemelä, Valter, Emami Khoonsari, Payam, Sundblom, Jimmy, Burman, Joachim, Landtblom, Anne-Marie, Spjuth, Ola, Nyholm, Dag, Kultima, Kim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411723/
https://ncbi.nlm.nih.gov/pubmed/30858393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40186-5
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