Cerebrospinal Fluid Biomarkers Link Toxic Astrogliosis and Microglial Activation to Multiple Sclerosis Severity

BACKGROUND: Once multiple sclerosis (MS) reaches the progressive stage, immunomodulatory treatments have limited efficacy. This suggests that processes other than activation of innate immunity may at least partially underlie disability progression during late stages of MS. Pathology identified these...

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Udgivet i:Mult Scler Relat Disord
Main Authors: Masvekar, Ruturaj, Wu, Tianxia, Kosa, Peter, Barbour, Christopher, Fossati, Valentina, Bielekova, Bibiana
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411304/
https://ncbi.nlm.nih.gov/pubmed/30553167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.msard.2018.11.032
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