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Ultra-high Resolution Band-Selective HSQC for Nanomole-Scale Identification of Chlorine-Substituted (13)C in Natural Products Drug Discovery

Ultra-high resolution band-selective HSQC (bsHSQC) has been employed for detection of (35)Cl-(37)Cl isotope shifted (13)C NMR signals for assignment of regioisomerism in bromo-chloro natural products. Optimum pulse sequence and instrumental parameters for maximization of detection of the isotope shi...

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Detalhes bibliográficos
Publicado no:Magn Reson Chem
Main Authors: Wang, Xiao, Duggan, Brendan M., Molinski, Tadeusz F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411301/
https://ncbi.nlm.nih.gov/pubmed/26951950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrc.4415
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