CoPhosK: A method for comprehensive kinase substrate annotation using co-phosphorylation analysis

We present CoPhosK to predict kinase-substrate associations for phosphopeptide substrates detected by mass spectrometry (MS). The tool utilizes a Naïve Bayes framework with priors of known kinase-substrate associations (KSAs) to generate its predictions. Through the mining of MS data for the collect...

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Publicado en:PLoS Comput Biol
Autores principales: Ayati, Marzieh, Wiredja, Danica, Schlatzer, Daniela, Maxwell, Sean, Li, Ming, Koyutürk, Mehmet, Chance, Mark R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411229/
https://ncbi.nlm.nih.gov/pubmed/30811403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006678
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