Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect

Benzodiazepines (BZDs) have been a standard treatment for anxiety disorders for decades, but the neuronal circuit interactions mediating their anxiolytic effect remain largely unknown. Here, we find that systemic BZDs modulate central amygdala (CEA) microcircuit activity to gate amygdala output. Com...

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Pubblicato in:Mol Psychiatry
Autori principali: Griessner, Johannes, Pasieka, Manuel, Böhm, Vincent, Grössl, Florian, Kaczanowska, Joanna, Pliota, Pinelopi, Kargl, Dominic, Werner, Barbara, Kaouane, Nadia, Strobelt, Sandra, Kreitz, Silke, Hess, Andreas, Haubensak, Wulf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411154/
https://ncbi.nlm.nih.gov/pubmed/30504824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0310-3
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