Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect

Benzodiazepines (BZDs) have been a standard treatment for anxiety disorders for decades, but the neuronal circuit interactions mediating their anxiolytic effect remain largely unknown. Here, we find that systemic BZDs modulate central amygdala (CEA) microcircuit activity to gate amygdala output. Com...

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Publicat a:Mol Psychiatry
Autors principals: Griessner, Johannes, Pasieka, Manuel, Böhm, Vincent, Grössl, Florian, Kaczanowska, Joanna, Pliota, Pinelopi, Kargl, Dominic, Werner, Barbara, Kaouane, Nadia, Strobelt, Sandra, Kreitz, Silke, Hess, Andreas, Haubensak, Wulf
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411154/
https://ncbi.nlm.nih.gov/pubmed/30504824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0310-3
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