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Molecular Biomarkers and Histological Parameters Impact on Survival and Response to First- Line Systemic Therapy of Metastatic Colorectal Cancer Patients

BACKGROUND: Histological parameters of primary tumour and nodal metastases are prognostic factors for survival of operable colorectal (CRC) patients, but not predictive for response rate of systemic therapy. KRAS mutations in codons 12 and 13 were first recognized as a predictive factor for resistan...

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Detalhes bibliográficos
Publicado no:Radiol Oncol
Main Authors: Rebersek, Martina, Mesti, Tanja, Boc, Marko, Ocvirk, Janja
Formato: Artigo
Idioma:Inglês
Publicado em: Sciendo 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411021/
https://ncbi.nlm.nih.gov/pubmed/30840593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/raon-2019-0013
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