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Beating the reaction limits of biosensor sensitivity with dynamic tracking of single binding events

The clinical need for ultrasensitive molecular analysis has motivated the development of several endpoint-assay technologies capable of single-molecule readout. These endpoint assays are now primarily limited by the affinity and specificity of the molecular-recognition agents for the analyte of inte...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Sevenler, Derin, Trueb, Jacob, Ünlü, M. Selim
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410873/
https://ncbi.nlm.nih.gov/pubmed/30782809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815329116
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