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Structural basis for activity of TRIC counter-ion channels in calcium release

Trimeric intracellular cation (TRIC) channels are thought to provide counter-ion currents that facilitate the active release of Ca(2+) from intracellular stores. TRIC activity is controlled by voltage and Ca(2+) modulation, but underlying mechanisms have remained unknown. Here we describe high-resol...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Xiao-hui, Su, Min, Gao, Feng, Xie, Wenjun, Zeng, Yang, Li, De-lin, Liu, Xue-lei, Zhao, Hong, Qin, Li, Li, Fei, Liu, Qun, Clarke, Oliver B., Lam, Sin Man, Shui, Guang-hou, Hendrickson, Wayne A., Chen, Yu-hang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410872/
https://ncbi.nlm.nih.gov/pubmed/30770441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817271116
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