Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication

Assembly of paramyxoviral nucleocapsids on the RNA genome is an essential step in the viral cycle. The structural basis of this process has remained obscure due to the inability to control encapsidation. We used a recently developed approach to assemble measles virus nucleocapsid-like particles on s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Desfosses, Ambroise, Milles, Sigrid, Jensen, Malene Ringkjøbing, Guseva, Serafima, Colletier, Jacques-Philippe, Maurin, Damien, Schoehn, Guy, Gutsche, Irina, Ruigrok, Rob W. H., Blackledge, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410849/
https://ncbi.nlm.nih.gov/pubmed/30787192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816417116
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