Early onset preeclampsia in a model for human placental trophoblast

We describe a model for early onset preeclampsia (EOPE) that uses induced pluripotent stem cells (iPSCs) generated from umbilical cords of EOPE and control (CTL) pregnancies. These iPSCs were then converted to placental trophoblast (TB) representative of early pregnancy. Marker gene analysis indicat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sheridan, Megan A., Yang, Ying, Jain, Ashish, Lyons, Alex S., Yang, Penghua, Brahmasani, Sambasiva R., Dai, Aihua, Tian, Yuchen, Ellersieck, Mark R., Tuteja, Geetu, Schust, Danny J., Schulz, Laura C., Ezashi, Toshihiko, Roberts, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410818/
https://ncbi.nlm.nih.gov/pubmed/30787190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816150116
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