Early onset preeclampsia in a model for human placental trophoblast

We describe a model for early onset preeclampsia (EOPE) that uses induced pluripotent stem cells (iPSCs) generated from umbilical cords of EOPE and control (CTL) pregnancies. These iPSCs were then converted to placental trophoblast (TB) representative of early pregnancy. Marker gene analysis indicat...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Sheridan, Megan A., Yang, Ying, Jain, Ashish, Lyons, Alex S., Yang, Penghua, Brahmasani, Sambasiva R., Dai, Aihua, Tian, Yuchen, Ellersieck, Mark R., Tuteja, Geetu, Schust, Danny J., Schulz, Laura C., Ezashi, Toshihiko, Roberts, R. Michael
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410818/
https://ncbi.nlm.nih.gov/pubmed/30787190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816150116
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