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Cell-intrinsic, Bmal1-dependent circadian regulation of temozolomide sensitivity in glioblastoma
The safety and efficacy of chemotherapeutics can vary as a function of the time of their delivery during the day. This study aimed to improve the treatment of glioblastoma (GBM), the most common brain cancer, by testing whether the efficacy of the DNA alkylator temozolomide (TMZ) varies with the tim...
Shranjeno v:
| izdano v: | J Biol Rhythms |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6410359/ https://ncbi.nlm.nih.gov/pubmed/28470120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0748730417696788 |
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