Neorogioltriol and Related Diterpenes from the Red Alga Laurencia Inhibit Inflammatory Bowel Disease in Mice by Suppressing M1 and Promoting M2-Like Macrophage Responses

Macrophages are central mediators of inflammation, orchestrating the inflammatory response through the production of cytokines and nitric oxide. Macrophages obtain pro-inflammatory (M1) and anti-inflammatory (M2) phenotypes, which can be modulated by soluble factors, including natural products. Desp...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Daskalaki, Maria G., Vyrla, Dimitra, Harizani, Maria, Doxaki, Christina, Eliopoulos, Aristides G., Roussis, Vassilios, Ioannou, Efstathia, Tsatsanis, Christos, Kampranis, Sotirios C.
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410277/
https://ncbi.nlm.nih.gov/pubmed/30717366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17020097
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