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Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents

Triterpenoid saponins from Saponinum album (SA) significantly augment the cytotoxicity of saporin-based immunotoxins but the mechanism of augmentation is not fully understood. We investigated the effects of six small molecule pharmacological agents, which interfere with endocytic and other processes...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxins (Basel)
Egile Nagusiak: Smith, Wendy S., Johnston, David A., Holmes, Suzanne E., Wensley, Harrison J., Flavell, Sopsamorn U., Flavell, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410249/
https://ncbi.nlm.nih.gov/pubmed/30791598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11020127
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