Duck Plague Virus Promotes DEF Cell Apoptosis by Activating Caspases, Increasing Intracellular ROS Levels and Inducing Cell Cycle S-Phase Arrest

Background: Duck plague virus (DPV) can induce apoptosis in duck embryo fibroblasts (DEFs) and in infected ducks, but the molecular mechanism of DPV-induced apoptosis remains unknown. Methods: We first used qRT-PCR and a Caspase-Glo assay to determine whether the caspase protein family plays an impo...

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Pubblicato in:Viruses
Autori principali: Zhao, Chuankuo, Wang, Mingshu, Cheng, Anchun, Yang, Qiao, Wu, Ying, Jia, Renyong, Zhu, Dekang, Chen, Shun, Liu, Mafeng, Zhao, Xinxin, Zhang, Shaqiu, Liu, Yunya, Yu, Yanling, Zhang, Ling, Tian, Bin, Rehman, Mujeeb Ur, Pan, Leichang, Chen, Xiaoyue
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409732/
https://ncbi.nlm.nih.gov/pubmed/30813500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11020196
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