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Design and Evaluation of An Extended-Release Olmesartan Tablet Using Chitosan/Cyclodextrin Composites

Sustained-release olmesartan tablets (OLM) were prepared by the simple, direct compression of composites of anionic sulfobutyl ether-β-cyclodextrin (SBE-β-CD) and cationic spray-dried chitosan (SD-CS), and were evaluated for use as a sustained release preparation for the treatment of hypertension. A...

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Vydáno v:Pharmaceutics
Hlavní autoři: Anraku, Makoto, Tabuchi, Ryo, Goto, Miwa, Iohara, Daisuke, Mizukai, Yasuyuki, Maezaki, Yuji, Michihara, Akihiro, Kadowaki, Daisuke, Otagiri, Masaki, Hirayama, Fumitoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409563/
https://ncbi.nlm.nih.gov/pubmed/30781383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11020082
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