A Single-Nucleotide Polymorphism of α(V)β(3) Integrin Is Associated with the Andes Virus Infection Susceptibility

The Andes Orthohantavirus (ANDV), which causes the hantavirus cardiopulmonary syndrome, enters cells via integrins, and a change from leucine to proline at residue 33 in the PSI domain (L33P), impairs ANDV recognition. We assessed the association between this human polymorphism and ANDV infection. W...

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Publicat a:Viruses
Autors principals: Martínez-Valdebenito, Constanza, Angulo, Jenniffer, Le Corre, Nicole, Marco, Claudia, Vial, Cecilia, Miquel, Juan Francisco, Cerda, Jaime, Mertz, Gregory, Vial, Pablo, Lopez-Lastra, Marcelo, Ferrés, Marcela
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409546/
https://ncbi.nlm.nih.gov/pubmed/30791508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11020169
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