Optical Quantal Analysis Using Ca(2+) Indicators: A Robust Method for Assessing Transmitter Release Probability at Excitatory Synapses by Imaging Single Glutamate Release Events

Despite evidence that presynaptic efficacy and plasticity influence circuit function and behavior in vivo, studies of presynaptic function remain challenging owing to the difficulty of assessing transmitter release in intact tissue. Electrophysiological analyses of transmitter release are indirect a...

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Bibliographic Details
Published in:Front Synaptic Neurosci
Main Authors: Padamsey, Zahid, Tong, Rudi, Emptage, Nigel
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409341/
https://ncbi.nlm.nih.gov/pubmed/30886576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2019.00005
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