Development of an orthotopic canine prostate cancer model expressing human GRPr

BACKGROUND: Ace-1 canine prostate cancer cells grow orthotopically in cyclosporine immunosuppressed laboratory beagles. We previously transfected (human Gastrin-Releasing Peptide Receptor, huGRPr) into Ace-1 cells and demonstrated receptor-targeted NIRF imaging with IR800-G-Abz4-t-BBN, an agonist to...

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Détails bibliographiques
Publié dans:Prostate
Auteurs principaux: Tweedle, Michael F., Ding, Haiming, Drost, William T., Dowell, Joshua, Spain, James, Joseph, Mathew, Elshafae, Said M., Menendez, Maria-Isabela, Gong, Li, Kothandaraman, Shankaran, Dirksen, Wessel P., Wright, Chadwick L., Bahnson, Robert, Knopp, Michael V., Rosol, Thomas J.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409197/
https://ncbi.nlm.nih.gov/pubmed/29992622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23686
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