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Leber's hereditary optic neuropathy: Severe vascular pathology in a severe primary mutation

The purpose of the present article was to evaluate the previously unreported vascular alterations in Leber's Hereditary Optic Neuropathy (LHON) 3460 mitochondrial DNA (mtDNA) mutation. Among the three primary mtDNA mutations, namely 11778, 14484, and 3460, LHON 3460 is the most rare and histori...

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Detalhes bibliográficos
Publicado no:Intractable Rare Dis Res
Main Authors: Asanad, Samuel, Meer, Elana, Tian, Jack J., Fantini, Michele, Nassisi, Marco, Sadun, Alfredo A.
Formato: Artigo
Idioma:Inglês
Publicado em: International Research and Cooperation Association for Bio & Socio-Sciences Advancement 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409112/
https://ncbi.nlm.nih.gov/pubmed/30881859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/irdr.2018.01126
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