Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult

OBJECTIVE: Diabetic polyneuropathy (DPN) is one of the most prevalent diabetic complications. We previously demonstrated that exendin-4 (Ex4), a glucagon-like peptide-1 receptor agonist (GLP-1RA), has beneficial effects in animal models of DPN. We hypothesized that GLP-1 signaling would protect neur...

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Publicat a:J Diabetes Res
Autors principals: Mohiuddin, Mohammad Sarif, Himeno, Tatsuhito, Inoue, Rieko, Miura-Yura, Emiri, Yamada, Yuichiro, Nakai-Shimoda, Hiromi, Asano, Saeko, Kato, Makoto, Motegi, Mikio, Kondo, Masaki, Seino, Yusuke, Tsunekawa, Shin, Kato, Yoshiro, Suzuki, Atsushi, Naruse, Keiko, Kato, Koichi, Nakamura, Jiro, Kamiya, Hideki
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408997/
https://ncbi.nlm.nih.gov/pubmed/30918901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9426014
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