The relative toxicity of brodifacoum enantiomers

Brodifacoum (BDF) is a potent, long-acting anticoagulant rodenticide that can cause fatal poisoning in humans. The chemical structure of BDF includes 2 chiral carbons, resulting in 2 pairs of diastereomers, BDF-cis (R/S and S/R) and BDF-trans (R/R and S/S). However, the relative potency of these mol...

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Detalhes bibliográficos
Publicado no:Toxicol Lett
Main Authors: Feinstein, Douglas L, Gierzal, Kamil, Iqbal, Asif, Kalinin, Sergey, Ripper, Richard, Lindeblad, Matthew, Zahkarov, Alexander, Lyubimov, Alexander, van Breemen, Richard, Weinberg, Guy, Rubinstein, Israel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408973/
https://ncbi.nlm.nih.gov/pubmed/30779948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2019.02.011
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