Synthesis and Pre-Clinical Characterization of a Cationic Iodinated Imaging Contrast Agent (CA4+) and Its Use for Quantitative Computed Tomography of Ex Vivo Human Hip Cartilage

Contrast agents that go beyond qualitative visualization and enable quantitative assessments of functional tissue performance represent the next generation of clinically useful imaging tools. An optimized and efficient large-scale synthesis of the cationic iodinated contrast agent (CA4+) is describe...

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Vydáno v:J Med Chem
Hlavní autoři: Stewart, Rachel C., Patwa, Amit N., Lusic, Hrvoje, Freedman, Jonathan D., Wathier, Michel, Snyder, Brian D., Guermazi, Ali, Grinstaff, Mark W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408935/
https://ncbi.nlm.nih.gov/pubmed/28616978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b00234
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