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Functional crosstalk across IMD and Toll pathways: insight into the evolution of incomplete immune cascades

In insects, antimicrobial humoral immunity is governed by two distinct gene cascades, IMD pathway mainly targeting Gram-negative bacteria and Toll pathway preferentially targeting Gram-positive bacteria, which are widely conserved among diverse metazoans. However, recent genomic studies uncovered th...

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Bibliografiske detaljer
Udgivet i:Proc Biol Sci
Main Authors: Nishide, Yudai, Kageyama, Daisuke, Yokoi, Kakeru, Jouraku, Akiya, Tanaka, Hiromitsu, Futahashi, Ryo, Fukatsu, Takema
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408883/
https://ncbi.nlm.nih.gov/pubmed/30963836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2018.2207
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