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Inferring the model and onset of natural selection under varying population size from the site frequency spectrum and haplotype structure

A fundamental question about adaptation in a population is the time of onset of the selective pressure acting on beneficial alleles. Inferring this time, in turn, depends on the selection model. We develop a framework of approximate Bayesian computation (ABC) that enables the use of the full site fr...

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Detalhes bibliográficos
Publicado no:Proc Biol Sci
Main Authors: Nakagome, Shigeki, Hudson, Richard R., Di Rienzo, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408616/
https://ncbi.nlm.nih.gov/pubmed/30963935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2018.2541
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