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Enterovirus particles expel capsid pentamers to enable genome release

Viruses from the genus Enterovirus are important human pathogens. Receptor binding or exposure to acidic pH in endosomes converts enterovirus particles to an activated state that is required for genome release. However, the mechanism of enterovirus uncoating is not well understood. Here, we use cryo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Buchta, David, Füzik, Tibor, Hrebík, Dominik, Levdansky, Yevgen, Sukeník, Lukáš, Mukhamedova, Liya, Moravcová, Jana, Vácha, Robert, Plevka, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408523/
https://ncbi.nlm.nih.gov/pubmed/30850609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09132-x
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