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Enterovirus particles expel capsid pentamers to enable genome release

Viruses from the genus Enterovirus are important human pathogens. Receptor binding or exposure to acidic pH in endosomes converts enterovirus particles to an activated state that is required for genome release. However, the mechanism of enterovirus uncoating is not well understood. Here, we use cryo...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Buchta, David, Füzik, Tibor, Hrebík, Dominik, Levdansky, Yevgen, Sukeník, Lukáš, Mukhamedova, Liya, Moravcová, Jana, Vácha, Robert, Plevka, Pavel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408523/
https://ncbi.nlm.nih.gov/pubmed/30850609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09132-x
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