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Global response of diacylglycerol kinase towards substrate binding observed by 2D and 3D MAS NMR

Escherichia coli diacylglycerol kinase (DGK) is an integral membrane protein, which catalyses the ATP-dependent phosphorylation of diacylglycerol (DAG) to phosphatic acid (PA). It is a unique trimeric enzyme, which does not share sequence homology with typical kinases. It exhibits a notable complexi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Möbius, Kristin, Kazemi, Sina, Güntert, Peter, Jakob, Andreas, Heckel, Alexander, Becker-Baldus, Johanna, Glaubitz, Clemens
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408475/
https://ncbi.nlm.nih.gov/pubmed/30850624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40264-8
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