Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

Scleroderma is an autoimmune rheumatic disorder accompanied by severe fibrosis in skin and other internal organs. During scleroderma progression, resident fibroblasts undergo activation and convert to α-smooth muscle actin (α-SMA) expressing myofibroblasts (MFBs) with increased capacity to synthesiz...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Park, Jong-Sung, Oh, Yumin, Park, Yong Joo, Park, Ogyi, Yang, Hoseong, Slania, Stephanie, Hummers, Laura K., Shah, Ami A., An, Hyoung-Tae, Jang, Jiyeon, Horton, Maureen R., Shin, Joseph, Dietz, Harry C., Song, Eric, Na, Dong Hee, Park, Eun Ji, Kim, Kwangmeyung, Lee, Kang Choon, Roschke, Viktor V., Hanes, Justin, Pomper, Martin G., Lee, Seulki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408468/
https://ncbi.nlm.nih.gov/pubmed/30850660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09101-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados