Joint contributions of rare CNVs and common SNPs to risk for schizophrenia

OBJECTIVE: Both rare copy number variants (CNVs) and common single nucleotide polymorphisms (SNPs) contribute to liability to schizophrenia, but their etiological relationship has not been fully elucidated. We evaluated an additive model, whereby risk of schizophrenia requires less contribution from...

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Publié dans:Am J Psychiatry
Auteurs principaux: Bergen, Sarah E., Ploner, Alexander, Howrigan, Daniel, O’Donovan, Michael C., Smoller, Jordan W., Sullivan, Patrick F., Sebat, Jonathan, Neale, Benjamin, Kendler, Kenneth S.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408268/
https://ncbi.nlm.nih.gov/pubmed/30392412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2018.17040467
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